Clinical Trial Sponsors: National Institutes of Health Clinical Center (CC)

  Source:		NCT00066209

     		Severe Acute Respiratory Syndrome (SARS)


			First Update August 5, 2003
			Last Update June 30, 2017

			Brief Summary
			Severe Acute Respiratory Syndrome (SARS) is
			a newly recognized illness that can be fatal. The
			purpose of this study is to better understand
			SARS by collecting samples of blood and other
			body fluids of people who have been exposed
			to SARS or who are suspected to have the
			illness. Up to 300 volunteers aged 18 years or
			older will be enrolled in this study. Participants
			will donate blood samples and, if appropriate,
			samples of fluid from the lungs, nose, or throat.
			Researchers will test these samples for
			proteins that control or mediate inflammatory or
			immune responses. The patterns of these
			proteins will reveal how SARS affects the body
			and the efforts the body makes to fight off the

			Detailed Description
			Severe acute respiratory syndrome (SARS) is a
			newly recognized illness associated with
			substantial mobidity and mortality. Patients
			develop fever followed by rapidly progressive
			and even fatal respiratory disease. SARS is
			associated with infection with a novel
			coronavirus. The evaluation of the
			inflammatory responses evoked by SARS may
			yield information regarding its pathogenesis and
			help with patient management. This protocol,
			then, merely aims to study disease
			pathogenesis and natural history, by studying
			samples and data that are collected by outside
			physicians or physicians at the Clinical Center
			and sent for evaluation of the inflammatory

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