Clinical Trial Sponsors

Heart Disease
University of California, San DiegoUniversity of Kentucky
Trial to Reduce Sitting Time in Postmenopausal Latina Women at Increased Risk for Heart Disease (Recruiting)Stem Cell Heart Injections During Laser Revascularization Surgery for Treatment of Chronic Ischemic Heart Disease (Recruiting)
National Institutes of Health Clinical Center (CC)Los Angeles Biomedical Research Institute
Diabetes and Heart Disease Risk in Blacks (Recruiting)Firefighter Aged Garlic Extract Investigation With CoQ10 as a Treatment for Heart Disease (FAITH) (Completed)

Heart Failure
University Hospital, CaenJordi Gol i Gurina Foundation
Bisoprolol Plasma Residual Concentrations in Chronic Heart Failure (Recruiting)Heart Failure STratification and OutcomeS (Recruiting)
The Cleveland ClinicFar Eastern Memorial Hospital
Virtual Visits in Heart Failure Care Transitions (Recruiting)The Role of Nuclear Imaging in Heart Failure (Recruiting)

Cardiac Arrhythmia
Texas Cardiac Arrhythmia Research FoundationNew York University School of Medicine
PV Reconnection After PVAI at Different Power Settings and Adenosine Provocation (Recruiting)Sparsity-based Magnetic Resonance Imaging of Cardiac Arrhythmias (Recruiting)
CyberHeart Inc.The Cleveland Clinic
CyberHeart's Cardiac Arrhythmia Ablation Treatment: Patients With Refractory Ventricular Tachycardia/Fibrillation (Recruiting)Biospecimen Repository for Cardiac Arrhythmias at the Cleveland Clinic (Recruiting)

University of Roma La SapienzaWinthrop University Hospital
Retinal Thrombosis and Atherosclerosis (Recruiting)Atherosclerosis in Rheumatoid Arthritis and Lupus: Restoring Cholesterol Balance (Recruiting)
Cedars-Sinai Medical CenterCedars-Sinai Medical Center
Atherosclerosis, Immune Mediated Inflammation and Hypoestrogenemia in Young Women (Recruiting)Pilot Study-Magnetic Resonance Imaging for Global Atherosclerosis Risk Assessment (Recruiting)

Coronary Artery Disease
James J. Peters Veterans Affairs Medical CenterCharite University, Berlin, Germany
Coronary Artery Calcification Score and Risk Factors for Coronary Artery Disease in Persons With Spinal Cord Injury (Recruiting)Diagnostic Imaging Strategies for Patients With Stable Chest Pain and Intermediate Risk of Coronary Artery Disease (Recruiting)
Aarhus University HospitalUniversity of Edinburgh
Coronary Artery Disease After Heart Transplantation (Recruiting)PET MRI in Coronary Artery Disease (Recruiting)

Left Ventricular Systolic Dysfunction
AmgenArmaron Bio Pty Ltd
A Study of Ivabradine in African-American/ Black Subjects With Heart Failure and Left Ventricular Systolic Dysfunction. (Recruiting)NP202 for Treatment of Post -STEMI Left Ventricular Systolic Dysfunction (Recruiting)
Flinders UniversityCentre Hospitalier Universitaire, Amiens
Cardiac Magnetic Resonance GUIDEd Management of Mild-moderate Left Ventricular Systolic Dysfunction. (Recruiting)Place of Echocardiography in IV Fluid Therapy in Patients With Septic Shock and Left Ventricular Systolic Dysfunction (Recruiting)

Left Ventricular Hypertrophy
Assiut UniversityUniversity of Virginia
Relationship of Different Electrocardiographic Parameters and Ambulatory Blood Pressure Parameters to Detect Left Ventricular Hypertrophy (Recruiting)HCMR - Novel Markers of Prognosis in Hypertrophic Cardiomyopathy (Active, not recruiting)
Hospital Universitari de BellvitgeNational Defense Medical Center, Taiwan
Everolimus and Tacrolimus Combination for Regression of Left Ventricular Hypertrophy in Renal Transplants (Recruiting)The Relationship Among, Serum Uric Acid, Left Ventricular Hypertrophy and Metabolic Syndrome (Recruiting)

Myocardial Infarction
University of AarhusCatholic University of the Sacred Heart
Rapid Use of High-sensitive Cardiac Troponin I for ruling-in and Ruling-out of Acute Myocardial Infarction (Recruiting)RIGENERA 2.0 Trial (Active, not recruiting)
IsalaCentre Hospitalier de la Région d'Annecy
The Effect of Opioids on P2Y12 Receptor Inhibition in Patients With ST-Elevation Myocardial Infarction Who Are Pre-treated With Crushed Ticagrelor (Recruiting)Quality and Safety of Initial Management for ST-segment Elevation Myocardial Infarction (Recruiting)

Heart Transplantation
Ottawa Heart Institute Research CorporationDr. F. Köhler Chemie GmbH
Cardiovascular Prehabilitation in Patients Awaiting Heart Transplantation (PREHAB HTx Study) (Recruiting)Study of Organ Perfusion With Custodiol-N Solution Compared With Custodiol Solution in Heart Transplantation (Recruiting)
University of PittsburghSemmelweis University
Administration of Prothrombin Complex Concentrate vs. Standard Transfusion During/After Heart Transplantation (Recruiting)Intraoperative Use of Extracorporeal Cytokine Adsorption During Orthotopic Heart Transplantation (Recruiting)

Institute for Clinical Effectiveness and Health PolicyVirginia Commonwealth University
Effect of Peer Mentoring and Blood Pressure Self-monitoring on Hypertension Control. (Recruiting)Vascular Responses to Sympathetic Activation and Altered Shear Rate: The Impact of Hypertension and Sodium Intake (Recruiting)
University of IndianapolisYonsei University
Effect of Occupational Therapy in Promoting Medication Adherence in Clients With Hypertension (Recruiting)Development of Diagnostic and Treatment Strategy for Resistant Hypertension (Recruiting)

National Institutes of Health Clinical Center (CC)Sheba Medical Center
Study of Lung Proteins in Patients With Pneumonia (Recruiting)PICR-b Nasopharyngeal S. Pneumoniae and Nasal S. Aureus Carriage Study (Recruiting)
Chongqing Medical UniversityUniversity Hospital, Grenoble
Biomarkers in Patients With Pneumonia (Recruiting)Non Invasive Diagnosis of Pneumocystis Pneumonia (Recruiting)

Respiratory Tract Infection
National Institute of Allergy and Infectious Diseases (NIAID)Universidad Nacional Autonoma de Mexico
A Randomized Double-Blinded, Placebo-Controlled Trial of Antibiotic Therapy in Patients With Lower Respiratory Tract Infection (LRTI) and a Procalcitonin Level (Recruiting)Probiotics, Respiratory and Intestinal Microbiome and Respiratory Tract Infections in Children (Recruiting)
Poitiers University HospitalMeMed Diagnostics Ltd.
Assessement of Viral Shedding Duration After a Respiratory Tract Infection in Oncology and Hematology Patients (Recruiting)Evaluating a Host-response Based Diagnostic for Distinguishing Between Bacterial and Viral Etiology in Patients With Lower Respiratory Tract Infection (LRTI) (Recruiting)

Respiratory Distress
Third Military Medical UniversityUniversity of Oklahoma
Establishment of a Biomarkers-based Early Warning System of Acute Respiratory Distress Syndrome (ARDS) (Recruiting)Fluid Restriction in Respiratory Distress of the Newborn (Recruiting)
Hospital Regional Rio GallegosChina-Japan Friendship Hospital
Abnormalities in Lung Computed Tomography and Physiological Alterations in Patients With Acute Respiratory Distress Syndrome (Recruiting)A Realworld Study of Acute Respiratory Distress Syndrome in China (Recruiting)

Respiratory Failure
Fondazione IRCCS Ca' Granda, Ospedale Maggiore PoliclinicoUniversity of Colorado, Denver
Sigh in Acute Hypoxemic Respiratory Failure (Recruiting)Aspiration in Acute Respiratory Failure Survivors (Recruiting)
Hôpital Louis MourierNHS Greater Glasgow and Clyde
Conduct of Nasal High Flow Oxygen in Acute Respiratory Failure (Recruiting)Flow veRsus OxygeNaTion In acutE ReSpiratory Failure (Recruiting)

Chronic Obstructive Pulmonary Disease
University of British ColumbiaPolitecnico di Milano
Chronic Obstructive Pulmonary Disease Biomarker Study (Recruiting)Monitoring Chronic Obstructive Pulmonary Disease Patients at Home by a Forced Oscillation Technique Device (Recruiting)
Politecnico di MilanoAsan Medical Center
Monitoring Chronic Obstructive Pulmonary Disease Patients at Home by a Forced Oscillation Technique Device (Recruiting)The Microbiome of Sputum, Urine and Feces in Healthy Persons and Chronic Obstructive Pulmonary Disease (COPD) Patients (Recruiting)

Pulmonary Function
Rush University Medical CenterPolarean Imaging Ltd.
The Accuracy of Smartphone Pulse Oximetry in Patients Visiting an Outpatient Pulmonary Function Lab for a 6-Minute Walk Test (Recruiting)Hyperpolarized Xenon MRI for Assessment of Pulmonary Function in Lung Transplant (Recruiting)
Tokat Gaziosmanpasa UniversityOslo University Hospital
The Effect of Anesthesia Type on Pulmonary Function (Recruiting)Fontan Circulation and Cardiopulmonary Function: Prognostic Factors, Hemodynamics and Long-term Effects (Recruiting)

Pulmonary Edema
Centre Hospitalier de la Région d'AnnecyCentre Chirurgical Marie Lannelongue
Management of Cardiogenic Pulmonary Edema (RENAU-OAP) (Recruiting)Evaluation of the Effectiveness of Non-invasive Ventilation on the Reperfusion Pulmonary Edema Post Pulmonary Artery Angioplasty in the Post Embolic Pulmonary Hypertension (Recruiting)
University Hospital, ToulouseUniversity Hospital, Montpellier
Performance Evaluation of Clinical Ultrasound in Management of Acute Pulmonary Edema in Elderly Patient (Recruiting)High Flow Nasal Oxygen Versus VNI in Acute Hypercapnic Cardiogenic Pulmonary Edema (Recruiting)

Small Cell Lung Cancer [video]
AbbVieGuizhou Medical University
A Study of SC-011 Alone and in Combination With ABBV-181 in Subjects With Relapsed or Refractory Small Cell Lung Cancer (Recruiting)Irinotecan Plus Lobaplatin Versus Irinotecan in the Second-line Treatment of Small Cell Lung Cancer (Recruiting)
Guizhou Medical UniversityVanderbilt-Ingram Cancer Center
Etoposide Plus Lobaplatin Versus Etoposide Plus Cisplatin for Patients With Limited Small-cell Lung Cancer (Recruiting)Tumor-Treating Fields Therapy in Preventing Brain Tumors in Participants With Extensive-Stage Small Cell Lung Cancer (Recruiting)

Non-Small Cell Lung Cancer [video]
Chinese Academy of Medical SciencesAbramson Cancer Center of the University of Pennsylvania
To Evaluate Postoperative 3D Conform Radiotherapy in Patients With IIIA (N2) Non-small Cell Lung Cancer (Recruiting)A Prospective Study of Electronic Symptom Reporting Via Mobile Phone Among Patients With Advanced Non-Small Cell Lung Cancer (Recruiting)
National Cheng-Kung University HospitalNational Institutes of Health Clinical Center (CC)
Comparison of Cost-effectiveness of Continuation Maintenance Therapy With Six Cycles of Pemetrexed Versus Pemetrexed Until Disease Progression for Metastatic Non-squamous Non-small-cell Lung Cancer (Recruiting)Molecular Profiling and Targeted Therapy for Advanced Non-Small Cell Lung Cancer, Small Cell Lung Cancer, and Thymic Malignancies (Recruiting)

Triple Negative Breast Cancer [video]
Mario Negri Institute for Pharmacological ResearchHospital General Universitario Gregorio Marañon
Neoadjuvant Zoledronate and Atorvastatin in Triple Negative Breast Cancer (Recruiting)Predictors of Response to Neoadjuvant Docetaxel-Carboplatin Chemotherapy for Patients With Stage II and III Triple Negative Breast Cancer (Recruiting)
OHSU Knight Cancer InstituteUniversity of Kansas Medical Center
Olaparib and Durvalumab in Treating Participants With Metastatic Triple Negative Breast Cancer (Recruiting)Neoadjuvant Phase II Study of Pembrolizumab And Carboplatin Plus Docetaxel in Triple Negative Breast Cancer (Recruiting)

Ovarian Cancer [video]
National University Hospital, SingaporeKazia Therapeutics Limited
Vinorelbine in Relapsed Platinum Resistant or Refractory C5 High Grade Serous, Endometrioid, or Undifferentiated Primary Peritoneum, Fallopian Tube or Ovarian Cancer (Recruiting)Phase I Study of Cantrixil in Patients With Ovarian Cancer, Fallopian Tube Cancer or Primary Peritoneal Cancer. (Recruiting)
Institut Paoli-CalmettesInstitut de Cancérologie de Lorraine
Genetic Predisposition to Breast and Ovarian Cancer: Prospective Study of BRCAx Gene Mutation (Recruiting)HE4 as a Relapse Biomarker in Ovarian Cancers (Recruiting)

Assistance Publique - Hôpitaux de ParisRadius Health, Inc.
Interest of Denosumab Treatment in Osteoporosis Associated to Systemic Mastocytosis (Recruiting)Safety and Efficacy of Abaloparatide-SC in Men With Osteoporosis (ATOM) (Recruiting)
University of PittsburghUniversity of Messina
Preventing Osteoporosis Using Denosumab (Recruiting)Effects of Genistein Aglycone in Glucocorticoid Induced Osteoporosis (Recruiting)

Postmenopausal Osteoporosis
Institut za Rehabilitaciju Sokobanjska BeogradSecond Affiliated Hospital of Soochow University
Influence of Exercise Program on Serum Matrix Metalloproteinases and Functional Status in Women With Postmenopausal Osteoporosis (Recruiting)The Deferasirox-calcium-vitamin D3 Therapy for Postmenopausal Osteoporosis (PMOP) (Recruiting)
Medical University of ViennaFujian Academy of Traditional Chinese Medicine
MiDeTe - microRNA Levels Under Denosumab and Teriparatide Therapy in Postmenopausal Osteoporosis (Recruiting)CLCF1 Gene Associated With Postmenopausal Osteoporosis of Kidney Yin Deficiency Syndrome (Recruiting)

Pregnancy [video]
Hospital de Santa Maria, PortugalStanford University
Sonographic Evaluation of Fetal Growth in the Third Trimester of Low-risk Pregnancy: a Randomized Trial (Recruiting)Correlation Between Oocyte and Embryo Mechanical Properties on Embryo Development and Clinical Pregnancy After In Vitro Fertilization (Enrolling by invitation)
The AlfredCHU de Reims
The National Register of Antipsychotic Medication in Pregnancy (NRAMP) (Recruiting)Pregnancy Denial and Attachment (Recruiting)

Renal Insufficiency
AllecraUniversity of Chicago
Pharmacokinetics of Cefepime and AAI101 in Subjects With Renal Insufficiency and Healthy Subjects (Recruiting)Circadian Function and Cardio-metabolic Risk in Adrenal Insufficiency (Recruiting)
Hospital Clinic of BarcelonaMassachusetts General Hospital
Comparative Study of the Efficacy of Oral Versus Intravenous Hydration as a Preventive Measure of Contrast-induced Nephropathy (CIN) in Patients With Renal Insufficiency (RI) Grade III Under Study Conducting Computed Tomography (CT) (Recruiting)A Study of Denosumab in Multiple Myeloma Patients With Renal Insufficiency (Recruiting)

Chronic Kidney Disease
University of Illinois at ChicagoJewish General Hospital
Resistance Exercise Training in Chronic Kidney Disease (Recruiting)Effect of Vitamin D3 Supplementation on Arterial and Bone Remodeling in Chronic Kidney Disease Patients (Recruiting)
Lawson Health Research InstituteUniversity Hospital, Toulouse
Micro-Particle Curcumin for the Treatment of Chronic Kidney Disease (Recruiting)Biomarkers of Cardiovascular Complications in Chronic Kidney Disease (Recruiting)

Kidney Transplantation [video] [video]
Odense University HospitalHansa Medical AB
Molecular Biological and Moleculargenetic Monitoring of Therapy After Kidney Transplantation (Recruiting)A Follow up Study of Patients Treated With Imlifidase Prior to Kidney Transplantation (Recruiting)
Hospital do Rim e HipertensãoSeoul National University Hospital
Comparison of the Efficacy and Safety of Sirolimus Versus Everolimus Versus Mycophenolate in Kidney Transplantation (Recruiting)Metabolite Biomarkers Related to Acute Rejection in Kidney Transplantation (Recruiting)

Gastroesophageal Reflux
McGuire Research InstituteMayo Clinic
Confocal Endomicroscopy for Permeability of Esophageal Wall in Refractory Gastroesophageal Reflux Disease (GERD) (Recruiting)Pharmacogenetic Testing in Children With Persistent Gastroesophageal Reflux Disease (Recruiting)
OHSU Knight Cancer InstituteUniversity of Colorado, Denver
Swallowable Sponge Cell Sampling Device and Next Generation Sequencing in Detecting Esophageal Cancer in Patients With Low or High Grade Dysplasia, Barrett Esophagus, or Gastroesophageal Reflux Disease (Recruiting)Precision Approach to PPI Therapy in Gastroesophageal Reflux Disease (Recruiting)

Russian Cardiology Research and Production CenterSanofi
Russian Familial Hypercholesterolemia Registry (Recruiting)An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia (Recruiting)
University of RostockRegeneron Pharmaceuticals
Biomarker for Homozygous Familial Hypercholesterolemia (Recruiting)Efficacy and Safety of Evinacumab in Patients With Homozygous Familial Hypercholesterolemia (Recruiting)

Shanghai Jiao Tong University School of MedicineFirst Affiliated Hospital of Harbin Medical University
The Effect of Omega-3 FA on Hypertriglyceridemia in Patients With T2DM(OCEAN) (Recruiting)Lipid-lowering Effects of Gefarnate in Statin-treated Coronary Heart Disease Patients With Residual Hypertriglyceridemia (Recruiting)
Regeneron PharmaceuticalsAkcea Therapeutics
Safety and Efficacy Following Repeat-Dose of Evinacumab (Anti-ANGPTL3) in Patients With Severe Hypertriglyceridemia (sHTG) at Risk for Acute Pancreatitis (Recruiting)Study of ISIS 703802 in Subjects With Hypertriglyceridemia, Type 2 Diabetes Mellitus, and Nonalcoholic Fatty Liver Disease (Recruiting)

Liver Cirrhosis
Postgraduate Institute of Medical Education and ResearchVinmec Research Institute of Stem Cell and Gene Technology
Growth Hormone Therapy in Liver Cirrhosis (Recruiting)Autologous Bone Marrow Mononuclear Stem Cell for Children Suffering From Liver Cirrhosis Due to Biliary Atresia (Recruiting)
Shanghai Zhongshan HospitalDayanand Medical College and Hospital
The Effect of Calcium β-hydroxy-β-methylbutyrate (CaHMB) Supplementation in Sarcopenia in Liver Cirrhosis (Recruiting)Sarcopenia Improves the Muscle Mass and Muscle Strength of Patients With Liver Cirrhosis-Child C (Recruiting)

Primary Biliary Cirrhosis
Mayo ClinicXijing Hospital of Digestive Diseases
Genetic Epidemiology of Primary Biliary Cirrhosis (PBC) (Recruiting)Fuzhenghuayu in Combination With Ursodeoxycholic Acid in Primary Biliary Cirrhosis (Recruiting)
Newcastle-upon-Tyne Hospitals NHS TrustInstituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
B-Cell Depleting Therapy (Rituximab) as a Treatment for Fatigue in Primary Biliary Cirrhosis (Completed)Use of Bezafibrate in Patients With Primary Biliary Cirrhosis to Archive Complete Biochemical Response in Non-responders (Recruiting)

Hepatocellular Carcinoma
Seoul National University HospitalEisai Inc.
Phase II Study of Avelumab in Patients With Advanced Hepatocellular Carcinoma After Prior Sorafenib Treatment (Recruiting)A Post-marketing Observational Study on Risk Factors for Hepatic Encephalopathy in Participants With Unresectable Hepatocellular Carcinoma (Recruiting)
King Saud UniversityTakeda
Mechanism of Sorafenib Resistance in Patients With Advanced Hepatocellular Carcinoma (Recruiting)A Phase 2 Study of Cabozantinib in Japanese Patients With Advanced Hepatocellular Carcinoma (Recruiting)

Liver Transplantation
Asan Medical CenterAkdeniz University
Effect of Preoperative Beta Blocker Use Postoperative Renal Function in the Patients Undergoing Liver Transplantation (Recruiting)S100β and Neuron Specific Enolase Levels in Liver Transplantation (Recruiting)
Federal University of Minas GeraisUniversity Hospital, Geneva
Evolution and Clinical Outcomes in Patients Undergoing Liver Transplantation (Recruiting)Immunity Against Varicella in Pediatric Orthotopic Liver Transplantation Recipients (Recruiting)

University of Texas Southwestern Medical CenterNational Institutes of Health Clinical Center (CC)
Active Preoperative Anemia Management in Patients Undergoing Cardiac Surgery (Recruiting)Eltrombopag for People With Fanconi Anemia (Recruiting)
American University of Beirut Medical CenterM.D. Anderson Cancer Center
Trial of Captafer® vs. Oral Iron Sulfate in the Treatment of Iron Deficiency Anemia in Patients With IBD (Recruiting)Efficacy of Ferric Carboxymaltose in Gastrointestinal Stromal Tumor (GIST) Patients With Iron Deficiency Anemia (IDA) Receiving Systemic Therapy (Recruiting)

Abbott NutritionAction Contre la Faim
Evaluation of a High Calorie, High Protein Tube Feeding Product in an Adult Population With or at Risk of Malnutrition (Recruiting)Biomedical Investigations for Optimized Diagnosis and Monitoring of Severe Acute Malnutrition (SAM): Elucidating the Heterogeneous Diagnosis of SAM by Current Anthropometric Criteria and Moving Beyond (Recruiting)
Oslo University HospitalEpicentre
Development of a Decision Support System to Prevent and Treat Disease-related Malnutrition (Recruiting)Reducing the Frequency of Follow up and Task Sharing in the Treatment of Uncomplicated Severe Acute Malnutrition (Recruiting)

Vitamin D Deficiency
Marmara UniversityIsfahan University of Medical Sciences
Central Sensitization in Vitamin D Deficiency (Recruiting)Vitamin D Deficiency Treatment Outcomes After Non-ST-Segment Elevation Myocardial Infarction (Recruiting)
King Saud UniversityUniversity of Nebraska
Vitamin D Supplementation to Prevent Vitamin D Deficiency for Children With Epilepsy (Recruiting)Cholecalciferol in Treating Patients With Newly Diagnosed Non-Hodgkin Lymphoma or Chronic Lymphocytic Leukemia With Vitamin D Deficiency (Recruiting)

Insulin Resistance
University Health Network, TorontoInstituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Stool Transplantation for Treatment of Insulin Resistance in Morbidly Obese Patients (Recruiting)Effect of Dietary Protein and Energy Restriction in the Improvement of Insulin Resistance in Subjects With Obesity (Recruiting)
Vanderbilt University Medical CenterChangi General Hospital
Contribution of Hyperinsulinemia vs. Hyperglycemia to Insulin Resistance in Type 1 Diabetes and Maturity Onset Diabetes of the Young, Type 2 (MODY2) (Recruiting)Comparing Effects of Liraglutide and Bariatric Surgery on Weight Loss, Liver Function, Body Composition, Insulin Resistance, Endothelial Function and Biomarkers of Non-alcoholic Steatohepatitis (NASH) in Obese Asian Adults (Recruiting)

First Affiliated Hospital of Chengdu Medical CollegeUniversity of Iowa
Fecal Microbiota Transplantation (FMT) for Severe Acute Pancreatitis(SAP) (Recruiting)Pediatric Longitudinal Cohort Study of Chronic Pancreatitis (Recruiting)
Kuopio University HospitalShaare Zedek Medical Center
Laparoscopic Cholecystectomy in Idiopathic Pancreatitis (Recruiting)Thiopurine Induced Pancreatitis in IBD Patients (Recruiting)

Diabetes Mellitus Type 2
Danish Pain Research CenterPila Pharma
Polyneuropathy in Diabetes Mellitus Type 2 (Recruiting)A Single-dose Trial to Investigate the Safety and Tolerability of XEN-D0501 in 24 Patients With Diabetes Mellitus Type 2 (Recruiting)
Cairo UniversityUniversidade Federal de Pernambuco
Detecting the Influence of Cataract Surgery on the Development of Diabetic Retinopathy in Patients With Diabetes Mellitus Type 2 With and Without Diabetic Retinopathy Using OCT Angiography (Recruiting)Effectiveness of Proprioceptive Training on Plantar Pressure, Balance, Posture and Gait in Individuals With Diabetes Mellitus Type 2 (Recruiting)

Diabetic Retinopathy
Centre Hospitalier Universitaire Saint PierreJohns Hopkins University
Role of Obstructive Sleep Apnea Syndrome in the Occurrence of Diabetic Retinopathy in Type 2 Diabetes. (Recruiting)Oxidative Stress In Stargardt Disease, Age Related Macular Degeneration and Diabetic Retinopathy (Recruiting)
Poitiers University HospitalTemple University
Safety and Efficacy of Aflibercept in Proliferative Diabetic Retinopathy. (Recruiting)Evaluation of Progression of Diabetic Retinopathy With Rapid Correction of Hyperglycemia (Recruiting)

Retinal Vein Occlusion
Shahid Beheshti University of Medical SciencesNational Institutes of Health Clinical Center (CC)
Comparison of Therapeutic Effects Between Intravitreal Injection of Bevacizumab With Intravitreal Injection of Bevacizumab and Targeted Laser Photocoagulation of Non Perfused Areas of Retina in Patients With Acute Retinal Vein Occlusion (Recruiting)Minocycline to Treat Central Retinal Vein Occlusion (Recruiting)
Odense University HospitalChengdu Kanghong Biotech Co.,Ltd.
Navigated Laser In Branch Retinal Vein Occlusion Study (Recruiting)Conbercept Ophthalmic Injection for Patients of Central Retinal Vein Occlusion (Recruiting)

Retinitis Pigmentosa
MeiraGTx UK II LtdHorama S.A.
Natural History Study of Patients With X-linked Retinal Dystrophy Associated With Mutations in Retinitis Pigmentosa GTPase Regulator (RPGR) (Recruiting)Safety and Efficacy Study in Patients With Retinitis Pigmentosa Due to Mutations in PDE6B Gene (Recruiting)
MeiraGTx UK II LtdApplied Genetic Technologies Corp
Gene Therapy for X-linked Retinitis Pigmentosa (XLRP) Retinitis Pigmentosa GTPase Regulator (RPGR) (Recruiting)Safety and Efficacy of rAAV2tYF-GRK1-RPGR in Subjects With X-linked Retinitis Pigmentosa Caused by RPGR-ORF15 Mutations (Recruiting)

Macular Degeneration [video]
University Hospital Inselspital, BerneCentre Hospitalier Intercommunal Creteil
The Role of the Gut Metagenome on the Development of Age Related Macular Degeneration (AMD) (Recruiting)Clinical and Genetic Analyzes of Age-related Macular Degeneration (Recruiting)
Lee's Pharmaceutical LimitedRibomic USA Inc
TAB014(Drug Code) in Wet( Neovascular)Age-related Macular Degeneration(AMD) Subjects (Recruiting)RBM-007 in Subjects witH ExudatIve Age-related Macular Degeneration (Recruiting)

Hearing Loss
University of Colorado, DenverMedical Corps, Israel Defense Force
High Dose Oral Steroids in Sudden Sensorineural Hearing Loss (Recruiting)Risk Factors for Hearing Loss as a Result of Exposure to Noise During Military Training in the IDF (Recruiting)
Groupe Hospitalier de la Rochelle Ré AunisWashington University School of Medicine
Age-related Hearing Loss and Lexical Disorders (Recruiting)Cochlear Implantation in Adults With Asymmetric Hearing Loss Clinical Trial (Recruiting)

Philipps University Marburg Medical CenterUniversity of California, Irvine
Neurofeedback for Tinnitus - Does Frequency Specificity Matter? (Recruiting)Acoustic and Electrical Stimulation for the Treatment of Tinnitus (Recruiting)
University of ArkansasUniversity College London Hospitals
Effect of rTMS on Resting State Brain Activity in Tinnitus (Recruiting)A Comparison of CBTi and Usual Treatment for Tinnitus Related Insomnia (Recruiting)

National Institutes of Health Clinical Center (CC)University of Calgary
Screening Protocol for Genetic Diseases of Allergic Inflammation (Recruiting)Prenatal Inflammation and Perinatal Outcomes (Recruiting)
University of CincinnatiTampere University Hospital
Pericardial Fat and Inflammation in HIV Patients and Controls (Recruiting)Inhaled Nebulised S(+)-Ketamine for Postoperative Analgesia (Withdrawn)

Rheumatoid Arthritis
University of NebraskaUniversidad de Antioquia
Treatment of Rheumatoid Arthritis With Methotrexate: Predictors of Response (Recruiting)Pharmacogenomic in Colombian Patients With Rheumatoid Arthritis (Recruiting)
SanofiHope Biosciences
Effect of Sarilumab on Patient-reported Outcomes in Patients With Active Rheumatoid Arthritis (Recruiting)A Clinical Trial to Determine the Safety and Efficacy of Hope Biosciences Autologous Mesenchymal Stem Cell Therapy (HB-adMSCs) for the Treatment of Rheumatoid Arthritis (Recruiting)

Systemic Lupus Erythematosus
National Institutes of Health Clinical Center (CC)Shanghai GeneChem Co., Ltd.
Aerobic Exercise in Women With Systemic Lupus Erythematosus (Recruiting)A Study of CD19 Redirected Autologous T Cells for CD19 Positive Systemic Lupus Erythematosus (SLE) (Recruiting)
GlaxoSmithKlineNorthwell Health
Safety and Effectiveness of Belimumab in Systemic Lupus Erythematosus Registry (Recruiting)Development of a Novel Glutamate Receptor Ligand for PET Scans in Neuropsychiatric Systemic Lupus Erythematosus (Recruiting)

Primary Immunodeficiency
National Institutes of Health Clinical Center (CC)Fred Hutchinson Cancer Research Center
The Mechanistic Biology of Primary Immunodeficiency Disorders (Recruiting)Fludarabine Phosphate, Cyclophosphamide, and Total-Body Irradiation Followed by Donor Bone Marrow Transplant and Cyclophosphamide, Mycophenolate Mofetil, Tacrolimus, and Sirolimus in Treating Patients With Primary Immunodeficiency Disorders or Noncancerous Inherited Disorders (Recruiting)
Kuwait Society for Allergy and Clinical ImmunologyBiotest Pharmaceuticals Corporation
Primary Immunodeficiency in Kuwait (Recruiting)A Study About Low Blood Pressure in Patients With Primary Immunodeficiency Disease Treated With Immune Globulin Products (Recruiting)

Meyer Children's HospitalMaimonides Medical Center
Randomized Crossover Trial for the Evaluation of the Possible Effects in the Intestine of Two Different Pharmaceutical Forms of L - Thyroxine in Patients With Primary Acquired Hypothyroidism (Recruiting)Mean Percentage of Levothyroxine Dosage Increase in Patients With Hypothyroidism Started on Enteral Feeding (Recruiting)
University of PennsylvaniaUniversity of Maryland
Mechanistic Study of Subclinical Hypothyroidism In the Elderly (Recruiting)Hypothyroidism Treated With Calcitonin (Recruiting)

Acute Lymphoblastic Leukemia
Alliance for Clinical Trials in OncologySt. Jude Children's Research Hospital
Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia (Recruiting)Total Therapy XVII for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia and Lymphoma (Recruiting)
Eastern Cooperative Oncology GroupSt. Jude Children's Research Hospital
Venetoclax and Vincristine Liposomal in Treating Patients With Relapsed or Refractory T-cell or B-cell Acute Lymphoblastic Leukemia (Recruiting)Postural Control Under Different Cognitive Loads in Adult Survivors of Acute Lymphoblastic Leukemia and Age-Matched Healthy Individuals (Recruiting)

Acute Myeloid Leukemia
Azienda Ospedaliera Spedali Civili di BresciaInstitute of Hematology & Blood Diseases Hospital
Next Generation Sequencing (NGS) in Familial Acute Myeloid Leukemia and Myelodisplastic Syndromes (Recruiting)The Efficiency of CAMS (Chinese Academy of Medical Sciences)-2016 Trial for Pediatric Acute Myeloid Leukemia (Recruiting)
PETHEMA FoundationM.D. Anderson Cancer Center
Diagnostic Platform to Perform Centralized and Standardized Rapid Molecular Diagnosis by Next Generation Sequencing (NGS) in Patients Diagnosed With Acute Myeloid Leukemia. (Recruiting)Fludarabine Phosphate, Cytarabine, Filgrastim-sndz, Gemtuzumab Ozogamicin, and Idarubicin Hydrochloride in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome (Recruiting)

Peripheral Neuropathy
Indiana UniversityLoma Linda University
Investigating the Preventative Ability of Massage Therapy on Paclitaxel Induced Peripheral Neuropathy (Recruiting)The Effects of Passive Vibration in Patients With Diabetic Peripheral Neuropathy (Recruiting)
Wake Forest University Health SciencesDana-Farber Cancer Institute
Acupuncture in Reducing Chemotherapy-Induced Peripheral Neuropathy in Participants With Stage I-III Breast Cancer (Recruiting)Evaluating a Clinician Support Algorithm to Enhance Implementation of Evidence-Based Chemotherapy-Induced Peripheral Neuropathy Assessment and Management Recommendations (Recruiting)

Oxford University Clinical Research Unit, VietnamAssistance Publique Hopitaux De Marseille
Leukotriene A4 Hydrolase Stratified Trial of Adjunctive Corticosteroids for HIV-uninfected Adults With Tuberculous Meningitis (Recruiting)Improving the Diagnosis of Meningitis in Emergency Rooms (Recruiting)
Centre Hospitalier Universitaire DijonAgence de Médecine Préventive, France
Adjunction of Daptomycin for the Treatment of Pneumococcal Meningitis (Recruiting)Surveillance of Hospitalised Pneumonia and Bacterial Meningitis in Tône District, Togo, 2010-2013 (Recruiting)

University of California, San FranciscoNational Institutes of Health Clinical Center (CC)
A Study of Varlilumab and IMA950 Vaccine Plus Poly-ICLC in Patients With WHO Grade II Low-Grade Glioma (LGG) (Recruiting)A Phase II Trial of the DNA Methyl Transferase Inhibitor, Guadecitabine (SGI-110), in Children and Adults With Wild Type GIST,Pheochromocytoma and Paraganglioma Associated With Succinate Dehydrogenase Deficiency and HLRCC-associated Kidney Cancer (Recruiting)
Basilea PharmaceuticaUniversity Hospital, Basel, Switzerland
Phase 1/2a Study of Oral BAL101553 in Adult Patients With Solid Tumors or Glioblastoma or High-grade Glioma (Recruiting)Glioma and Exercising (Recruiting)

Glioblastoma Multiforme
Centre Antoine LacassagneUniversitätsmedizin Mannheim
Phase I/II Study of Pazopanib+ Temozolomide in Patients With Newly Diagnosed Glioblastoma Multiforme (Recruiting)Intraoperative Radiotherapy in Newly Diagnosed Glioblastoma Multiforme (Recruiting)
University of IowaUniversity of Sao Paulo
A Phase 2 Trial of High-Dose Ascorbate in Glioblastoma Multiforme (Recruiting)Hypofractionated Stereotactic Radiotherapy in Recurrent Glioblastoma Multiforme (Recruiting)

Intellectual Disability
Centre Hospitalier Universitaire de BesanconInstitut National de la Santé Et de la Recherche Médicale, France
Molecular Diagnosis of Syndromic or Isolated Severe Intellectual Disability Using Whole Exome Sequencing : a Pilot Study (Recruiting)Research and Characterization of New Genes Involved in Intellectual Disability (Recruiting)
Leiden University Medical CenterUniversity of Novi Sad
Reducing Aggression Among People With an Intellectual Disability (Recruiting)Dental Treatment and Oral Rehabilitation for Adult Individuals With Intellectual Disability in General Anaesthesia (Recruiting)

University of IowaThe Hong Kong Polytechnic University
Anxiety-mediated Impairments in Large Elastic Artery Function and the Autonomic Nervous System (Recruiting)Self-acupressure for Cancer-related Symptom Cluster of Insomnia, Depression, and Anxiety: a Feasibility Study (Recruiting)
Universitaet InnsbruckUniversity of Malaya
Motivation and Barriers for Exercise in Patients With Anxiety or Posttraumatic Stress Disorder (Recruiting)The Influence of Communication After Placement of Orthodontic Fixed Appliances on Pain, Anxiety and Oral Health Quality of Life Among Malaysian Population (Recruiting)

Psychiatric Hospital of the University of BaselTampere University Hospital
Probiotic Supplementation in Severe Depression (Recruiting)Inhaled Nebulised S(+)-Ketamine for Postoperative Analgesia (Withdrawn)
Johns Hopkins UniversityEmory University
Neuroimaging Epigenetics of Prospective Postpartum Depression Biomarkers (Recruiting)Inflammation-Induced CNS Glutamate Changes in Depression (Recruiting)

Major Depressive Disorder
University of CincinnatiNaurex, Inc, an affiliate of Allergan plc
Spinal Cord Stimulation for the Treatment of Major Depressive Disorder (Recruiting)A Study of Rapastinel as Adjunctive Therapy in Major Depressive Disorder (RAP-MD-03) (Recruiting)
Tel Aviv UniversityNeurolief Ltd.
Gaze Contingent Feedback in Major Depressive Disorder (MDD) (Recruiting)Safety and Feasibility of Combined Trigeminal and Occipital Transcutaneous Nerve Stimulation (CTO-TNS) in Major Depressive Disorder (MDD) (Recruiting)

Florida A&M UniversityChinese University of Hong Kong
Intervention of Attenuated Psychosis Syndrome With M-Health Technology (Recruiting)Social Impairment and Social Inappropriate Behavior in Patients With First Episode Psychosis: A Caregivers' Perspective (Recruiting)
Hartford HospitalNew York State Psychiatric Institute
Neurofeedback Training for High Risk Psychosis (Recruiting)Treatment of Psychosis and Agitation in Alzheimer's Disease (Recruiting)

VA Office of Research and DevelopmentPhilipps University Marburg Medical Center
Predictors of Response to Insomnia Treatments for Gulf War Veterans (Recruiting)Non-deceptive Application of Placebos in Insomnia (Recruiting)
University of Missouri-ColumbiaAalborg Universitetshospital
Insomnia Treatment and Problems (the iTAP Study) (Recruiting)Music to Improve Sleep Quality in Adults With Depression and Insomnia (Recruiting)

Sleep Apnea
VA Office of Research and DevelopmentHarokopio University
Influence of Exercise, Weight Loss, and Exercise Plus Weight Loss on Sleep Apnea (Recruiting)Mediterranean Lifestyle Intervention in Patients With Obstructive Sleep Apnea (Recruiting)
Johns Hopkins UniversityHospital Universitario La Paz
Predicting Risk Factors in Children With Obstructive Sleep Apnea Undergoing Adenotonsillectomy Surgery (Recruiting)CPAP Effect on Albuminuria in Patients With Diabetic Nephropathy and Obstructive Sleep Apnea (Recruiting)

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